External Contamination in Single Cell mtDNA Analysis
نویسندگان
چکیده
منابع مشابه
External Contamination in Single Cell mtDNA Analysis
BACKGROUND Mitochondrial DNA (mtDNA) variation in single hematopoietic cells, muscle fibers, oocytes, and from tiny amount of tumor tissues and degraded clinical specimens has been reported in many medical publications. External DNA contamination, notoriously difficult to avoid, threatens the integrity of such studies. METHODOLOGY/PRINCIPAL FINDINGS Employing a phylogenetic approach, we analy...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2007
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0000681